大鼠、小鼠睡眠剝奪儀是一款不需要對動物進行訓練以溫和的方式對動物進行睡眠限制的儀器。 參數設定完成后不需要人為的干預即可對大鼠或小鼠進行睡眠剝奪的實驗。可用于睡眠研究、時差研究和間斷性睡眠模型模擬。

產品特點

· 具有四種工作模式常開、定時、間歇、正反轉；

· 轉棒轉動溫和不會對動物造成任何機械損傷；

· 定時模式可設置干擾棒轉動的時間；

· 間歇模式可分別調節轉動時間和停止時間；

· 正反轉模式可以定時設置干擾棒的運轉方向；

· 轉棒高度可調減少墊料的影響；

· 根據實驗需求選配大鼠型、小鼠型活動籠；

· 我們也可以提供定制化改進服務；

型號YAN-239

可根據需要選擇水槽式睡眠剝奪箱

型號SY-M3100小鼠6個平臺

           SY-M3040小鼠40個平臺

           SY-R3020大鼠15個平臺

           更多型號請

小鼠的水槽式睡眠和疲勞剝奪正在進行中

部分參考文獻

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2. Hines, D.J., Schmitt, L.I., Hines, R.M., Moss, S.J., & Haydon, P.G. (2013). Antidepressant effects of sleep deprivation require astrocyte-dependent adenosine mediated signaling. Translational Psychiatry, 3, e212. doi10.1038/tp.2012.136

3. Lee, D., Lee, S., & Sohn, D. (2016). MP86-19 effect of sleep deprivation on hormonal axis and erectile function. Journal of Urology, 195(4), e1113. doi:10.1016/j.juro.2016.02.2327

4. Lee, D.S., Sohn, D.W., Yoon, B.I., & Yoo, J.M. (2017). 383 effect of sleep deprivation on hormonal axis and erectile function. Journal of Sexual Medicine, 14(1), S113-S114. doi10.1016/j.jsxm.2016.11.264

5. Naidoo, N., Davis, J.G., Zhu, J., Yabumoto, M., Singletary, K., Brown, M., … & Baur, J.A. (2014). Aging and sleep deprivation induce the unfolded protein response in the pancreasimplications for metabolism. Aging Cell, 13(1), 131-141. doi10.1111/acel.12158

6. Schmidt, M.A. & Wisor, J.P. (2012). Interleukin 1 receptor contributes to methamphetamine- and sleep deprivation-induced hypersomnolence. Neuroscience Letters, 513(2), 209-213. doi10.1016/j.neulet.2012.02.040

7. Ward, C.P., Wooden, J.I., & Kieltyka, R. (2017). Effects of sleep deprivation on spatial learning and memory in juvenile and young adult rats. Psychology & Neuroscience, 10(1), 109-116. doi10.1037/pne0000075

8. Wooden, J., Pido, J., Mathews, H., Kieltyka, R., Montemayor, B., & Ward, C. (2014). Sleep deprivation impairs recall of social transmission of food preference in rats. Nature and Science of Sleep, 2014(6), 129-135. doi10.2147/NSS.S68611

9. Duncan, M. J., L. E. Guerriero, K. Kohler, L. E. Beechem, B. D. Gillis, F. Salisbury, C. Wessel, J. Wang, S. Sunderam, A. D. Bachstetter, B. F. O’Hara and M. P. Murphy, 2022. Chronic Fragmentation of the Daily Sleep-Wake Rhythm Increases Amyloid-beta Levels and Neuroinflammation in the 3xTg-AD Mouse Model of Alzheimer’s Disease. Neuroscience 481111-122.

10. Robinson-Junker, A., O’Hara, B., Durkes, A., Gaskill, B., 2019. Sleeping through anythingThe effects of unpredictable disruptions on mouse sleep, healing, and affect. PloS one 14, e0210620.